EEG-defined subtypes of ADHD in adults
Attention-deficit hyperactivity disorder (ADHD) is a common and clinically heterogeneous disorder that is associated with considerable social costs. It is estimated that up to more than one half of ADHD children continue to manifest symptoms in adulthood. Over the past decades, electrophysiological research has produced a great amount of qEEG and ERP information about children and adolescents with ADHD. In recent years, several studies have identified subgroups of ADHD children with distinct EEG profiles, suggesting that children with a diagnosis of ADHD may constitute a heterogeneous group with different underlying electrophysiological abnormalities. The planned study is aimed to investigate the presence of EEG and ERP clusters within a sample of adults with attention-deficit hyperactivity disorder. The identification of distinct EEG-defined subgroups of adults with ADHD would have considerable implications for the use of EEG in the assessment and diagnosis of ADHD. The EEG will be recorded in a resting coniition, as well as while performing continuous performance tasks. Clinical subjects will be grouped by means of cluster analysis.
The study is accepted by MC of cost B27 and granted by Swiss state for three years.
Management: Brain- and trauma-foundation Grison, Switzerland
Workgroup: Dr. Andreas Müller, Gian Candrian, Dr. Eric Thomann, Dr. Bettina Bardill
Cooperation Partners: University of Trondheim (NO), Prof. Knut Hestad,University of Skopje (Macedonia), Prof. Nada Pop Jordanova. Other partners are welcome.